Mount Allison Chemistry Department

Research Interests

My research is concerned with the synthesis of small molecules with novel molecular scaffolds that have potential as bioactive agents in the treatment of disease. Modern methods of synthesis are routinely employed, including solid phase and microwave assisted techniques. As the synthetic routes can be novel, isotopic labelling and spectroscopic methods of analysis constitute a part of the research effort.

Currently, thermodynamically stable Meisenheimer and Janovsky complexes and protease-resistant peptoids are being pursued and tested in cell culture tests.



Home \| People

Academic Staff

	Dr. Adrian Culf
	BSc (Hons), PhD Surrey (UK)
	Assistant Professor

	Office:	Barclay 117
	Phone:	(506)364-2128
	Email:	aculf@mta.ca
	Discipline:	Organic Chemistry
	Research Area:	Medicinal and Physical Organic Chemistry


Research Interests My research is concerned with the synthesis of small molecules with novel molecular scaffolds that have potential as bioactive agents in the treatment of disease. Modern methods of synthesis are routinely employed, including solid phase and microwave assisted techniques. As the synthetic routes can be novel, isotopic labelling and spectroscopic methods of analysis constitute a part of the research effort. Currently, thermodynamically stable Meisenheimer and Janovsky complexes and protease-resistant peptoids are being pursued and tested in cell culture tests.

Recent Publications "Fast Deprotection of Synthetic Oligodeoxyribonucleotides using Standard Reagents under Microwave Irradiation" A.S. Culf, M. Cuperlovic-Culf, M. Laflamme, B.J. Tardiff, R.O. Ouellette, Oligonucleotides (in press). “Carbohydrate Microarrays: Survey of Fabrication Techniques” A.S. Culf, M. Cuperlovic-Culf, R.J. Ouellette, OMICS: A Journal of Integrative Biology, 10, 289-310 (2006). “Microarray Analysis of Alternative Splicing” M. Cuperlovic-Culf, N. Belacel, A.S. Culf, R.J. Ouellette, OMICS: A Journal of Integrative Biology, 10, 344-357 (2006). “Data analysis of alternative splicing microarrays” M. Cuperlovic-Culf, N. Belacel, A.S. Culf, R.J. Ouellette, Drug Discovery Today, 11(21-22), 983-90 (2006).

Chemistry Society \| Faculty of Science \| Mount Allison University

© 2007 Mount Allison University