Fraser Clark

Assistant professor

Fraser Clark

Contact Information

E-mail
fclark@mta.ca
Phone
(506) 364-2623
Office
Hart Hall 419
Office hours
Other websites

I am a molecular immunologist working on a variety of animal species to examine the amazing diversity and pathogen targeting ability of innate immune molecules. I examine host-pathogen-environment interactions between a variety of marine pathogens, their hosts and their ever-changing environment. My work focuses on crustacean and mollusk species that are commercially and ecologically important to Atlantic Canada and the Northeastern US. I use next-generation sequencing, bioinformatic, in vitro and in vivo experimental tools to answer complex biological questions, and put genomic and transcriptomic data in a biological and physiological context.  

 

Education

2016-Present Assistant Professor, Department of Chemistry and Biochemistry, Mount Allison University

2013-2016 Research Scientist/ Postdoc, AVC Lobster Science Centre, Biomedical Sciences, University of Prince Edward Island

2009-2013 PhD Pathology and Microbiology, University of Prince Edward Island

2002-2004 MSc, Pathology and Molecular Medicine, Queens University

1997-2002 BSc, Biochemistry and Molecular Biology, Dalhousie University

Teaching


2017-2018
• BIOL 2201 - Form and Function: Microorganisms
• BIOC/BIOL 3051 - Molecular Immunology
• BIOC 3111 - Environmental Microbiology
• BIOC/BIOL 4903 - Independent Study in Biochemistry or Biology
• BIOC 4903 - Current Advances in Biochemistry


2016-2017
• BIOC 1001 - Introductory Biochemistry
• BIOC/BIOL 3051 - Molecular Immunology
• BIOC/BIOL 3901 - Bioinformatic Analysis for Life Scientists
• BIOC 4903 - Independent Study in Biochemistry
• BIOC 4903 - Current Advances in Biochemistry

Publications

Book Chapter

K. F. Clark, 2016. Nimaviruses of Crustaceans, in: F Kibenge, M. Godoy, (Eds.), Aquaculture Virology. Elsevier Inc., New York. 

Peer-Reviewed Publications

K. F. Clark, J. Yang, A. R. Acorn, J. J. Garland, S. E. Stewart-Clark, S. J. Greenwood (2017) The impact of harvesting location on American lobster (Homarus americanus) during live storage. Journal of Crustacean Biology. 37 303-314.

J. Bojko, K. F. Clark, D. Bass, A. M. Dunn, S. E. Stewart-Clark, P. D. Stebbing, G. D. Stentiford. (2016) Parahepatospora carcini n. gen., n. sp., a parasite of invasive Carcinus maenas with intermediate features of sporogony between the Enterocytozoon clade and other Microsporidia. Journal of Invertebrate Pathology. 143 124-134.

L. Benestan, J-S. Moore, B. J. G. Sutherland, J. L. Luyer, H. Maaroufi, C. Rougeux, E. Normandeau, N. Rycroft, J. Atema, L. N. Harris, R. F. Tallman, S. J. Greenwood, K. F. Clark, L. Bernatchez. (2017) Sex matters in massive parallel sequencing: Evidence for biases in genetic parameter estimation and investigation of sex determination systems. Molecular Ecology in press.
 
 L. Benestan, B. K. Quinn, H. Maaroufi, M. Laporte, K. F. Clark, S. J. Greenwood. R. Rochette, L. Bernatachez. (2016) Seascape genomics provides evidence for thermal adaption and current-mediated poplation structure in American lobster (Homarus americanus). Molecular Ecology 25 5073-5092.
 
 K. F. Clark, S. J. Greenwood (2016) Next-generation sequencing and the crustacean immune system: the need for alternatives in immune gene annotation. Integrative and Comparative Biology, Integrative and Comparative Biology 56 1113-1130.
 
 K. F. Clark, D. Wadowska, S. J. Greenwood. (2016) Aerococcus viridans var. homari: the presence of capsule and the relationship to virulence in American lobster (Homarus americanus). Journal of Invertebrate Pathology, 133, 20-26.
 
 K. F. Clark, A. R. Acorn, H. Wang, S. J. Greenwood. (2015) Comparative tissue expression of American lobster (Homarus americanus) immune genes during bacterial and scuticociliate challenge. Fish and Shellfish Immunology, 47, 1054-1066.
 
 C. E. Davies, A. F. Johnson, E. C. Wootton, S. J. Greenwood, K. F. Clark, C. L. Vogan, A. F. Rowley. (2014) High population densities may lead to injury-induced disease within a temperate No-Take Zone. ICES Journal of Marine Science. doi:10.1093.
 
 K. F. Clark. (2014) Characterization and functional classification of American lobster (Homarus americanus) immune factor transcripts. Fish and Shellfish Immunology 41 12-26.
 
 K. F. Clark, P. Byrne, A. R. Acorn, S. J. Greenwood. (2013) Molecular immune response of the American lobster (Homarus americanus) to the White Spot Syndrome Virus. Journal of Invertebrate Pathology 114 298-308.
  
K. F. Clark, A. R. Acorn, S. J. Greenwood. (2013) A transcriptomic analysis of American lobster (Homarus americanus) immune response during infection with the bumper car parasite Anophryoides haemophila. Developmental and Comparative Immunology 40 112-122.
 
 K. F. Clark, A. R. Acorn, S. J. Greenwood. (2013) Differential expression of American lobster (Homarus americanus) immune related genes during infection of Aerococcus viridans var. homari, the causative agent of Gaffkemia. Journal of Invertebrate Pathology 112 192-202.
  
D. Hines, K. F. Clark, S. J. Greenwood. (2013) Global gene expression profiling of American lobster, Homarus americanus, larval stages during development and metamorphosis. Invertebrate Reproduction and Development 58 97-107.
 
 M. Bauer, S. J. Greenwood, K. F. Clark, P. Jackman, W. Fairchild. (2013) Analysis of gene expression in Homarus americanus larvae exposed to sublethal concentrations of endosulfan during metamorphosis. Comparative Biochemistry and Physiology Part D 8 300-308.
 
 M. AboElkhair, T. Iwamoto, K. F. Clark, P. McKenna, A. Siah, S. J. Greenwood, F. C. J. Berthe, J. W. Casey, A. Cepica. (2011) Lack of detection of a putative retrovirus associated with haemic neoplasia in the soft shell clam Mya arenaria. Journal of Invertebrate Pathology 109 97-104.
 
 K. F. Clark, S. J. Greenwood. (2011) Aerococcus viridans expression of Cpn60 is associated with virulence during infection of the American lobster Homarus americanus. Journal of Fish Diseases 34 831-843.
 
 A. G. Acorn, K. F. Clark, S. Jones; B. Despres, S. Munro, R. Cawthorn, S. J. Greenwood. (2011) Analysis of Expressed Sequence Tags (ESTs) and gene expression changes under different growth conditions for the ciliate Anophryoides haemophila, the causative agent of bumper car disease in the American lobster (Homarus americanus). Journal of Invertebrate Pathology 107 146-154.
 
 J. VanLeeuwen, S. J. Greenwood, K. F. Clark, A. Acorn, F. Markham, J. McCarron, R. O’Handley. (2011) Monensin use against Neospora caninum challenge in dairy cattle. Veterinary Parasitology 175 372-376.

M. AboElkhair, A. Siah, K. F. Clark, P. McKenna, J. Pariseau, S. J. Greenwood, F. C. J. Berthe, A. Cepica. (2009) Reverse transcriptase activity associated with haemic neoplasia in the soft-shell clam Mya arenaria. Diseases of Aquatic Organisms 84 57-63.